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The No.1 Research Site For Therapeutic Peptides


Thymosin Beta 4 10mg


Thymosin Beta 4 10mg

TB4, also known as Thymosin Beta 4 (Tβ4), is a synthetic version of a naturally occurring peptide found in nearly all animal cells. It is a 43-amino acid peptide with a variety of biological activities, including promoting wound healing, tissue repair, angiogenesis (formation of new blood vessels), and reducing inflammation. TB4 has been studied for its potential therapeutic applications in various fields, such as tissue regeneration and injury recovery.

Previous and ongoing research on TB4 has focused on several key areas:

  1. Wound healing and tissue repair: TB4 has been shown to promote wound healing and tissue repair in animal models by enhancing cell migration, angiogenesis, and collagen production. Research has been conducted on its potential use in treating skin injuries, burns, and muscle damage.
  2. Anti-inflammatory effects: TB4 has demonstrated anti-inflammatory properties by modulating the production of cytokines, which are involved in the inflammatory response. This has led to interest in its potential use in the treatment of inflammatory conditions and tissue damage.
  3. Cardiovascular protection: TB4 has been shown to protect cardiac tissue from damage and promote repair following injury, suggesting potential therapeutic applications in cardiovascular diseases.
  4. Nervous system protection and repair: TB4 has been studied for its potential neuroprotective effects, such as promoting neurite outgrowth and improving functional recovery after spinal cord injury in animal models.

Current research on TB4 is focused on further understanding its mechanisms of action, optimizing its therapeutic applications, and investigating its safety and efficacy in various populations and medical conditions. Some recent research papers related to TB4 include:

  1. Philp, D., et al. (2018). “Thymosin β4: Roles in Development, Repair, and Engineering of the Cardiovascular System.” Vitamins and Hormones, 107, 119-146. [This review paper discusses the roles of Thymosin Beta 4 in cardiovascular development, repair, and potential therapeutic applications.]
  2. Zhang, Z., et al. (2017). “Thymosin β4 promotes the survival and angiogenesis of transplanted endothelial progenitor cells in the infarcted myocardium.” International Journal of Molecular Medicine, 39(4), 979-987. [This study investigates the potential of TB4 to promote the survival and angiogenesis of transplanted endothelial progenitor cells in infarcted myocardium.]
  3. Shi, G., et al. (2016). “Thymosin β4 has a major role in dermal burn wound healing that involves actin cytoskeletal remodelling via heat-shock protein 70.” Journal of Tissue Engineering and Regenerative Medicine, 10(12), E521-E530. [This study explores the role of TB4 in dermal burn wound healing and its relationship with actin cytoskeletal remodeling and heat-shock protein 70.]
  4. Bock-Marquette, I., et al. (2014). “Thymosin β4 mediated PKC activation is essential to initiate the embryonic coronary developmental program and epicardial progenitor cell activation in adult mice in vivo.” Journal of Molecular and Cellular Cardiology, 69, 98-106. [This study investigates the role of TB4 in coronary development and epicardial progenitor cell activation in adult mice.]

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Professor of Neurobiology at Stanford University