TB500 (frag 17-23) 10mg
INTRODUCING
TB500 (frag 17-23) 10mg
TB-500 is a synthetic version of a fragment of Thymosin Beta-4 (Tβ4), a naturally occurring peptide found in nearly all animal cells. TB-500 is designed to mimic some of the biological activities of Tβ4, including promoting wound healing, tissue repair, angiogenesis (formation of new blood vessels), and reducing inflammation. It is often used for research and therapeutic applications due to its ease of synthesis and lower cost compared to the full-length Tβ4 peptide.
Previous and ongoing research on TB-500 has focused on several key areas:
- Wound healing and tissue repair: TB-500 has been shown to promote wound healing and tissue repair in animal models by enhancing cell migration, angiogenesis, and collagen production. Research has been conducted on its potential use in treating skin injuries, burns, and muscle damage.
- Anti-inflammatory effects: TB-500 has demonstrated anti-inflammatory properties by modulating the production of cytokines, which are involved in the inflammatory response. This has led to interest in its potential use in the treatment of inflammatory conditions and tissue damage.
- Cardiovascular protection: TB-500 has been shown to protect cardiac tissue from damage and promote repair following injury, suggesting potential therapeutic applications in cardiovascular diseases.
- Nervous system protection and repair: TB-500 has been studied for its potential neuroprotective effects, such as promoting neurite outgrowth and improving functional recovery after spinal cord injury in animal models.
Current research on TB-500 is focused on further understanding its mechanisms of action, optimizing its therapeutic applications, and investigating its safety and efficacy in various populations and medical conditions. Some recent research papers related to TB-500 include:
- Philp, D., et al. (2018). “Thymosin β4: Roles in Development, Repair, and Engineering of the Cardiovascular System.” Vitamins and Hormones, 107, 119-146. [This review paper discusses the roles of Thymosin Beta 4 and its fragments, including TB-500, in cardiovascular development, repair, and potential therapeutic applications.]
- Sosne, G., et al. (2015). “Thymosin β4 and a synthetic peptide containing its actin-binding domain promote dermal wound repair in db/db diabetic mice and in aged mice.” Annals of the New York Academy of Sciences, 1351(1), 45-56. [This study investigates the effects of Thymosin β4 and a synthetic peptide, which may include TB-500, on dermal wound repair in diabetic and aged mice.]
- Bock-Marquette, I., et al. (2014). “Thymosin β4 mediated PKC activation is essential to initiate the embryonic coronary developmental program and epicardial progenitor cell activation in adult mice in vivo.” Journal of Molecular and Cellular Cardiology, 69, 98-106. [This study investigates the role of Thymosin β4 and its fragments, including TB-500, in coronary development and epicardial progenitor cell activation in adult mice.]
5. Peptide delivery: Semax is typically administered as a nasal spray, which allows the peptide to bypass the blood-brain barrier and reach the central nervous system more effectively. Research is ongoing to develop more effective and convenient methods of delivering Semax, such as oral formulations or alternative routes of administration.