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ARA-290 8mg


ARA-290 8mg

ARA-290 is a synthetic peptide derived from the naturally occurring erythropoietin (EPO). Unlike EPO, ARA-290 does not stimulate red blood cell production, but it retains the tissue-protective and anti-inflammatory properties of EPO. ARA-290 is an 11-amino acid peptide that has been investigated for its potential therapeutic effects in various medical conditions, including peripheral neuropathy, kidney injury, and inflammatory diseases.

Previous and ongoing research on ARA-290 has focused on several key areas:

  1. Neuropathy: ARA-290 has been studied for its potential neuroprotective and regenerative effects in peripheral neuropathy, particularly in the context of diabetes and chemotherapy-induced neuropathy.
  2. Kidney injury: ARA-290 has demonstrated potential therapeutic effects in animal models of acute kidney injury and chronic kidney disease, and its anti-inflammatory and tissue-protective properties may contribute to its renal benefits.
  3. Inflammatory diseases: ARA-290 has been investigated for its potential anti-inflammatory effects and its ability to modulate immune response, with potential applications in conditions such as rheumatoid arthritis and inflammatory bowel disease.

Current research on ARA-290 is focused on further understanding its mechanisms of action, optimizing its therapeutic applications, and investigating its safety and efficacy in various populations and medical conditions. Some recent research papers related to ARA-290 include:

  1. Heij, L., et al. (2017). “Safety and efficacy of ARA 290 in sarcoidosis patients with symptoms of small fiber neuropathy: a randomized, double-blind pilot study.” Molecular Medicine, 23, 1-8. [This study evaluates the safety and efficacy of ARA-290 in sarcoidosis patients with symptoms of small fiber neuropathy.]
  2. Brines, M., & Cerami, A. (2012). “The receptor that tames the innate immune response.” Molecular Medicine, 18, 486-496. [This review paper discusses the role of the innate repair receptor, which is targeted by ARA-290, in modulating the innate immune response.]
  3. Collino, M., et al. (2011). “Treatment with the Erythropoietin-derived Peptide ARA290 Improves Systolic Function and Reduces Ventricular Fibrosis in Rats with Ischaemic Heart Failure.” Journal of Pharmacy and Pharmacology, 63(4), 535-542. [This study investigates the potential effects of ARA-290 on systolic function and ventricular fibrosis in rats with ischemic heart failure.]

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Function Medicine Coach and Health Optimiser

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Biohacker and Health Expert

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Professor of Neurobiology at Stanford University